Serveur d'exploration Chloroquine

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Sarcoidosis treated with chloroquine

Identifieur interne : 003E28 ( Main/Exploration ); précédent : 003E27; suivant : 003E29

Sarcoidosis treated with chloroquine

Auteurs : D. Davies [Royaume-Uni]

Source :

RBID : ISTEX:B8699D2F25BBCF05E540D6683B12362502335C8F

Descripteurs français

English descriptors

Abstract

Summary: Though the majority of patients with sarcoidosis need no treatment, some do because of the development of pulmonary fibrosis, bronchial obstruction or eye and skin lesions. The only well-tried treatment is the use of corticosteroids, which are attended by side effects and risks when continued for long periods.Five cases of pulmonary sarcoidosis, in which spontaneous regression was not expected, were treated with chloroquine. The drug produced or maintained regression of the lesions, but the effect may have been suppressive rather than curative. It may prove to be a better and safer alternative than corticosteroids.Bleaching of the hair appears to be an inevitable side effect and watch should be kept for eye complications.

Url:
DOI: 10.1016/S0007-0971(63)80005-4


Affiliations:


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Le document en format XML

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<term>Bronchial biopsy</term>
<term>Bronchial obstruction</term>
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<term>Bronchogram</term>
<term>Chloroquine</term>
<term>Chloroquine sulphate</term>
<term>Conjunctival biopsy</term>
<term>Corticosteroid</term>
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<term>Safer alternative</term>
<term>Sarcoid follicles</term>
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<term>Troublesome cough</term>
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